In urine, O-dealkyl and N-deethyl-O-dealkyl metabolites and glucuronides were being predominant. Isotonitazene and metonitazene O-dealkyl metabolites ended up the same molecules and may also be probable produced through the metabolization of structural analogues like etonitazene, protonitazene, or butonitazene, whose only variation from isotonitaze